Outcome of IVF in patients with endometriosis in comparison with tubal-factor infertility
Outcome of IVF in patients with endometriosis in comparison with tubal-factor infertility
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DOI：
10.1023/a:1022526002421
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发表时间：
1998-10-01
影响因子：
3.1
通讯作者：
Hillensjo, T
中科院分区：
文献类型：
--
作者：
Bergendal, A;Naffah, S;Hillensjo, T
目的：本回顾性研究的目的是比较子宫内膜异位症女性和输卵管因素不孕对照组的体外受精和胚胎移植结果。方法：48 名子宫内膜异位症患者在胡丁格大学医院接受了 65 个周期的体外受精和胚胎移植。患有输卵管因素不孕症的对照组由 98 名患者组成，共 98 个周期。对这些群体的刺激、受精、胚胎发育、着床和妊娠结局进行回顾性分析。结果：子宫内膜异位症女性的受精率显着较低，但卵裂率、着床率和妊娠率没有差异。结论：我们的结果表明，与输卵管女性相比，子宫内膜异位症女性的受精率较低；不孕因素然而，一旦卵母细胞受精，前胚胎似乎有正常的机会。着床，导致相似的妊娠率。
Purpose: The aim of this retrospective study was to compare the outcome of in vitro fertilization and embryo transfer in women with endometriosis and a control group with tubal-factor infertility.Methods: Forty-eight patients with endometriosis underwent 65 cycles of in vitro fertilization and embryo transfer at Huddinge University Hospital. The marched control group with tubal-factor infertility consisted of 98 cycles in 98 patients. These groups were retrospectively analyzed regarding stimulation,fertilization, embryo development,implantation, and pregnancy outcome.Results: The fertilization rate was significantly lower in women with endometriosis, but the cleavage, implantation, and pregnancy rates did not differ.Conclusions: Our results show that women with endometriosis have a lower fertilization rate compared with women with tubal;factor infertility However once the oocyte is fertilized, it seems that the preembryo has a normal chance of implantation, leading to similar pregnancy rates.