Putative spinal interneurons mediating postural limb reflexes provide a basis for postural control in different planes.
Putative spinal interneurons mediating postural limb reflexes provide a basis for postural control in different planes.
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DOI：
10.1111/ejn.12780
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发表时间：
2015-01
期刊：
影响因子：
--
通讯作者：
Deliagina TG
中科院分区：
文献类型：
--
作者：
Zelenin PV;Hsu LJ;Lyalka VF;Orlovsky GN;Deliagina TG
The dorsal-side-up trunk orientation in standing quadrupeds is maintained by the postural system driven mainly by somatosensory inputs from the limbs. Postural limb reflexes (PLRs) represent a substantial component of this system. Earlier we described spinal neurons presumably contributing to the generation of PLRs. The first aim of the present study was to reveal trends in the distribution of neurons with different parameters of PLR-related activity across the gray matter of the spinal cord. The second aim was to estimate the contribution of PLR-related neurons with different patterns of convergence of sensory inputs from the limbs to stabilization of body orientation in different planes. For this purpose, the head and vertebral column of the decerebrate rabbit were fixed, whereas the hindlimbs were positioned on a platform. Activity of individual neurons from L5–L6 was recorded during PLRs evoked by lateral tilts of the platform. In addition, the neurons were tested by tilts of the platform under only the ipsilateral or only the contralateral limb, as well as during in-phase tilts of the platforms under both limbs. We found that, across the spinal gray matter, strength of PLR-related neuronal activity and sensory input from the ipsi-limb decreased in the dorso-ventral direction, while strength of the input from the contra-limb increased. A near linear summation of tilt-related sensory inputs from different limbs was found. Functional roles were proposed for individual neurons. The obtained data present the first characterization of posture-related spinal neurons, forming a basis for studies of postural networks impaired by injury.
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影响因子：
5.7
作者：
Deliagina TG;Zelenin PV;Orlovsky GN
通讯作者：
Orlovsky GN
影响因子：
5.5
作者：
Bannatyne, B. A.;Liu, T. T.;Maxwell, D. J.
通讯作者：
Maxwell, D. J.
影响因子：
2.5
作者：
Bosco, G;Poppele, RE
通讯作者：
Poppele, RE
影响因子：
5.5
作者：
Deliagina, Tatiana G.;Sirota, Mikhail G.;Beloozerova, Irina N.
通讯作者：
Beloozerova, Irina N.
影响因子：
2.5
作者：
Deliagina, TG;Orlovsky, GN;Arshavsky, YI
通讯作者：
Arshavsky, YI