Immunolocalization of VR1 and VRL1 in rat larynx
Immunolocalization of VR1 and VRL1 in rat larynx
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DOI：
10.1016/j.autneu.2004.11.003
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发表时间：
2005-01-15
影响因子：
2.7
通讯作者：
Taniguchi, K
中科院分区：
文献类型：
--
作者：
Yamamoto, Y;Taniguchi, K
本文观察了大鼠喉组织中香草酸受体亚型1（VR 1）及其类似物香草酸受体样蛋白1（VRL 1）的免疫反应性，并结合P物质（SP）和降钙素基因相关肽（CGR-P）的免疫反应性。VR 1和VRL 1在喉上皮内游离神经末梢、上皮下神经丛和喉上皮细胞中均有表达。大多数VR 1免疫反应神经也对SP或CGRP呈免疫反应。VR 1免疫反应阳性的上皮内神经末梢可能是喉伤害感受器。(C)2004 Elsevier B. V.保留所有权利。
Immunoreactivity for vanilloid receptor subtype 1 (VR1) and its analogue vanilloid receptor-like protein 1 (VRL1) were examined in combination with immunoreactivity for substance P (SP) and calcitonin gene-related peptide (CGR-P) in the rat larynx. VR1 and VRL1 immunoreactivity were observed in the intraepithelial free nerve endings, subepithelial nerve plexus and laryngeal epithelial cells. Most of VR1 immunoreactive nerves were also immunoreactive for SP or CGRP. VR1 immunoreactive intraepithelial nerve endings may be laryngeal nociceptors. (C) 2004 Elsevier B.V. All rights reserved.