Epicardial adipose tissue is an independent predictor of coronary atherosclerotic burden
Epicardial adipose tissue is an independent predictor of coronary atherosclerotic burden
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DOI：
10.1016/j.ijcard.2010.12.085
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发表时间：
2012-06-28
影响因子：
3.5
通讯作者：
Gama, V.
中科院分区：
文献类型：
--
作者：
Bettencourt, N.;Toschke, A. M.;Gama, V.
前言：心外膜脂肪组织(EAT)在冠状动脉疾病(CAD)的发生发展中可能起积极作用。本研究的目的是通过多层螺旋CT评价EAT、腹部内脏脂肪(AVF)和冠状动脉粥样硬化负荷之间的关系。结果：215例患者平均年龄58±11岁，其中男性61%，平均体重指数(BMI)28±4 kg/m(2例)。进食量与男性、年龄、BMI、腹围、AVF、冠状动脉有斑块的节段数直接相关(P
Introduction: Epicardial adipose tissue (EAT) may play an active role in the development of coronary artery disease (CAD). The aim of this work was to study the relations between EAT, abdominal visceral fat (AVF), and coronary atherosclerotic burden as assessed by multislice computed tomography (MSCT).Population and methods: Two hundred fifteen patients without known CAD referred to 64-SCT during a 6-months period were included. All patients underwent a standardized protocol including quantification of AVF, EAT, coronary artery calcification (CAC), and coronary angiography by MSCT.Results: Two hundred fifteen patients, with mean age of 58 +/- 11 years, in which 61% were males, with mean body mass index (BMI) of 28 +/- 4 kg/m(2) were included. EAT volume was directly associated with male sex, age, BMI, abdominal circumference, AVF, number of coronary segments with atherosclerotic plaques (p