Risk factors and predictors of compliance in depression
Risk factors and predictors of compliance in depression
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DOI：
10.1016/s0924-977x(03)00095-6
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发表时间：
2003-09-01
影响因子：
5.6
通讯作者：
Demyttenaere, K
中科院分区：
文献类型：
--
作者：
Demyttenaere, K
自然主义研究表明，抗抑郁药治疗的平均时间不到6个月，而且停药率很高，特别是在初级保健抑郁症患者中。导致治疗中止的因素是多种多样的，而且了解不多。停药在治疗的第一个月最常见，在治疗过程中，流行的原因各不相同。大约25%的患者没有通知医生停止服用抗抑郁药物。最近的研究提供了新的信息，可以作为改善遵守的指导方针。医患关系，包括医生解释预期治疗时间和可能的不良反应所需的时间，是一个关键因素。医生对药物的态度也很重要。策略应适应治疗阶段，因为停药的常见原因会随着治疗进展而变化。(C)2003年由Elsevier B. V.出版/ ECNP。All rights reserved.
Naturalistic studies show that the average length of antidepressant treatment is less than 6 months and that discontinuations are high, especially in primary care depressed patients. Factors leading to treatment discontinuation are multiple and poorly understood. Discontinuations are most frequent during the first month of therapy, and the prevalent reasons vary during the course of therapy. Approximately 25% of patients do not inform their physician about stopping their antidepressant medication. Recent research provides new information that may serve as a guideline for improving compliance. The physician-patient relationship, including the amount of time the physician takes to explain the expected duration of treatment and possible adverse effects, is a key factor. The physician's attitude about the medication is also important. Strategies should be adapted to the stage of treatment, as common reasons for discontinuation change as treatment progresses. (C) 2003 Published by Elsevier B.V./ECNP. All rights reserved.