Differences in brachial and femoral artery responses to prolonged sitting
Differences in brachial and femoral artery responses to prolonged sitting
复制标题
肱动脉和股动脉对长时间坐着的反应存在差异
作者：
Saurabh S. Thosar;Sylvanna L. Bielko;C. Wiggins;J. Wallace
长时间坐着对肱动脉（BA）和股浅动脉（SFA）的影响是否相似，目前尚不清楚长时间坐着对血管功能是否存在肢体差异。参与3小时长时间静坐试验（SIT）。SFA和BA流量介导的扩张（FMD）和各自的流量模式进行了测量，在基线，1小时，2小时和3 hr.ResultsBy单因素方差分析有一个显着下降，SFA FMD在3小时的SIT（p < 0.001）。同时，顺行（p = 0.04）和平均（0.037）剪切率显著下降。通过单因素方差分析，在3小时的坐姿期间，BA FMD没有显著差异。除了坐位3小时期间顺行剪切率显著降低（p = 0.029）和振荡剪切指数显著增加（p = 0.034）外，BA中的剪切率无变化。此外，有BA和SFA FMD measurement.ConclusionThree小时的坐姿导致受损的SFA FMD，但没有BA FMD之间没有相关性。虽然3小时的坐姿并没有损害BA FMD，但它损害了BA的剪切模式。
IntroductionIt is unknown if there are limb differences in vascular function during prolonged sitting.PurposeThis study was designed to test whether the effects of prolonged sitting on brachial artery (BA) and the superficial femoral artery (SFA) are similar.MethodsTwelve men (24.2 ± 4 yrs.) participated in a 3 hr prolonged sitting trial (SIT). SFA and BA flow mediated dilation (FMD) and respective flow patterns were measured at baseline, 1 hr, 2 hr and 3 hr.ResultsBy a one-way ANOVA there was a significant decline in SFA FMD during 3 hrs of SIT (p < 0.001). Simultaneously, there was a significant decline in antegrade (p = 0.04) and mean (0.037) shear rates. By a one way ANOVA there were no significant differences in BA FMD during 3 hrs of sitting. There were no changes in the shear rates in the BA except for a significant decrease in antegrade shear rate (p = 0.029) and a significant increase in oscillatory shear index (p = 0.034) during 3 hrs of sitting. Furthermore, there was no correlation between BA and SFA FMD measurements.ConclusionThree hours of sitting resulted in impaired SFA FMD but not BA FMD. Although 3 hours of sitting did not impair BA FMD, it impaired shear patterns in the BA.
影响因子：
5
作者：
Matthews, Charles E.;Chen, Kong Y.;Troiano, Richard P.
通讯作者：
Troiano, Richard P.
健康老年人股动脉中促动脉粥样硬化的剪切率模式。
影响因子：
5.3
作者：
Young,ColinN;Deo,ShekharH;Padilla,Jaume;Laughlin,MHarold;Fadel,PaulJ
通讯作者：
Fadel,PaulJ
DOI：
10.1152/ajpheart.01133.2009
发表时间：
2010-04-01
影响因子：
4.8
作者：
Padilla, Jaume;Young, Colin N.;Fadel, Paul J.
通讯作者：
Fadel, Paul J.