Genetic variation for life history sensitivity to seasonal warming in Arabidopsis thaliana.
Genetic variation for life history sensitivity to seasonal warming in Arabidopsis thaliana.
复制标题
拟南芥对季节性变暖的遗传变异对季节性变暖的敏感性。
DOI：
10.1534/genetics.113.157628
复制
发表时间：
2014-02
期刊：
影响因子：
3.3
通讯作者：
Borevitz JO
中科院分区：
文献类型：
--
作者：
Li Y;Cheng R;Spokas KA;Palmer AA;Borevitz JO
气候变化改变了许多植物物种的生活史事件，然而，很少有人知道的遗传变异的季节性热响应。在这项研究中，我们模拟了当前和未来三个变暖的气候，并测量了开花时间在全球不同的拟南芥加入。我们发现，昼夜和季节温度升高（1°-3°）减少了两个秋季队列的开花时间。初秋队列的独特之处在于揭示了快速循环和越冬生活史策略;温度每升高1°，快速循环植物的比例增加3-7%。我们进行了全基因组关联研究（GWAS），以确定潜在的遗传基础的热敏感性。GWAS鉴定了5个控制开花时间的主效数量性状基因座（QTL）和另外5个具有热敏感性的QTL。候选基因包括已知的开花基因座;与热休克蛋白90相互作用的辅伴侣;和开花激素赤霉酸，一种生物合成酶。所鉴定的遗传结构允许准确预测开花表型（R2 > 0.95），其具有用于未来环境的适应性基因型的基因组选择的应用。本研究可为环境变化下的育种和保护遗传学研究提供参考。
Climate change has altered life history events in many plant species; however, little is known about genetic variation underlying seasonal thermal response. In this study, we simulated current and three future warming climates and measured flowering time across a globally diverse set of Arabidopsis thaliana accessions. We found that increased diurnal and seasonal temperature (1°–3°) decreased flowering time in two fall cohorts. The early fall cohort was unique in that both rapid cycling and overwintering life history strategies were revealed; the proportion of rapid cycling plants increased by 3–7% for each 1° temperature increase. We performed genome-wide association studies (GWAS) to identify the underlying genetic basis of thermal sensitivity. GWAS identified five main-effect quantitative trait loci (QTL) controlling flowering time and another five QTL with thermal sensitivity. Candidate genes include known flowering loci; a cochaperone that interacts with heat-shock protein 90; and a flowering hormone, gibberellic acid, a biosynthetic enzyme. The identified genetic architecture allowed accurate prediction of flowering phenotypes (R2 > 0.95) that has application for genomic selection of adaptive genotypes for future environments. This work may serve as a reference for breeding and conservation genetic studies under changing environments.