Fast and localized event-related optical signals (EROS) in the human occipital cortex: Comparisons with the visual evoked potential and fMRI
Fast and localized event-related optical signals (EROS) in the human occipital cortex: Comparisons with the visual evoked potential and fMRI
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DOI：
10.1006/nimg.1997.0298
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发表时间：
1997-10-01
期刊：
影响因子：
5.7
通讯作者：
Gratton, E
中科院分区：
文献类型：
--
作者：
Gratton, G;Fabiani, M;Gratton, E
在本研究中，视觉刺激在枕叶皮层引发的快速EROS反应（潜伏期约为100 ms）与fMRI信号在空间上一致，与vep在时间上一致，从而将亚厘米空间定位与亚秒时间分辨率结合起来。纹状体和纹状体外皮层的fMRI信号显示，在刺激后的不同潜伏期（分别为100和200-300 ms），这两个区域都出现了EROS峰值，表明EROS表现出与信息处理相关的局部神经元活动。该信号的时间分辨率和空间定位使其成为研究局部脑区活动时间过程的有前途的工具，并弥合了电成像和血流动力学成像方法之间的差距。(C) 1997学术出版社。
Localized evoked activity of the human cortex produces fast changes in optical properties that can be detected noninvasively (event-related optical signal, or EROS), In the present study a fast EROS response (latency approximate to 100 ms) elicited in the occipital cortex by visual stimuli showed spatial congruence with fMRI signals and temporal correspondence with VEPs, thus combining subcentimeter spatial localization with subsecond temporal resolution. fMRI signals were recorded from striate and extrastriate cortex, Both areas showed EROS peaks, but at different latencies after stimulation (100 and 200-300 ms, respectively), These results suggest that EROS manifests localized neuronal activity associated with information processing. The temporal resolution and spatial localization of this signal make it a promising tool for studying the time course of activity in localized brain areas and for bridging the gap between electrical and hemodynamic imaging methods. (C) 1997 Academic Press.