An Overoxidized Polypyrrole/Dodecylsulfonate Micelle Composite Film for Amperometric Serotonin Sensing
An Overoxidized Polypyrrole/Dodecylsulfonate Micelle Composite Film for Amperometric Serotonin Sensing
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DOI：
10.1149/1.1566420
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发表时间：
2003-05
影响因子：
3.9
通讯作者：
H. Shiigi;K. Okamura;Daisuke Kijima;B. Deore;U. Sree;T. Nagaoka
中科院分区：
文献类型：
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作者：
H. Shiigi;K. Okamura;Daisuke Kijima;B. Deore;U. Sree;T. Nagaoka
描述了一种基于过氧化聚吡咯（oPPy）修饰电极的5-羟色胺电流型传感器。以十二烷基磺酸盐胶束掺杂聚吡咯为氧化剂，通过电化学氧化法制备了聚吡咯复合膜。差示脉冲伏安法表明，涂有复合膜的玻碳电极对神经递质5-羟色胺的灵敏度比裸玻碳电极高约4倍，线性响应范围为1 ~ 100 μM（相关系数为0.996）。该修饰电极对痕量5-羟色胺的测定具有良好的重现性和稳定性（检测限：1 μM）。
An amperometric serotonin (5-hydroxytryptamine) sensor, based on an overoxidized polypyrrole (oPPy) modified electrode, is described. An oPPy composite film has been electrochemically synthesized through overoxidation of polypyrrole doped with a dodecylsulfonate micelle, Although the oPPy composite film was electroinactive, differential pulse voltammetry revealed that a glassy carbon (GC) electrode coated with the composite film had about four-fold higher sensitivity toward the neurotransmitter serotonin than a bare GC electrode with a linear response range of 1 to 100 μM (a correlation coefficient of 0.996). The oPPy modified electrode showed excellent reproducibility and stability for determination of serotonin at trace level concentrations (detection limit: I μM).