Topographic location of unisolated pontine infarction
Topographic location of unisolated pontine infarction
复制标题
DOI：
10.1186/s12883-019-1411-6
复制
发表时间：
2019-08-05
期刊：
影响因子：
2.6
通讯作者：
Jiang, Yongjun
中科院分区：
文献类型：
--
作者：
Huang, Jiehong;Qiu, Zhihua;Jiang, Yongjun
背景急性脑桥梗死的局部位置与临床症状和预后有关。以往的研究主要集中在孤立性脑桥梗死，但非孤立性脑桥梗死的局部位置仍不清楚。方法本研究为前瞻性、多中心、纵向登记研究。入选了经磁共振成像（MRI）证实的急性脑桥梗死患者。根据脑桥动脉的分布范围，将其分为前内侧、前外侧、被盖、双侧和单侧多发性梗死。结果自2003年5月1日至2017年10月31日，共纳入1003例患者，其中330例为非孤立性桥脑梗死。在孤立性脑桥梗死中，前内侧、前外侧、被盖、双侧和单侧多发性脑桥梗死分别占44.9%、19.8%、16.0%、13.1%和6.2%。在非孤立性脑桥梗死中，前内侧、前外侧、被盖、双侧和单侧多发性脑桥梗死分别占30.3%、19.7%、24.5%、15.2%和10.3%。结论非孤立性桥脑梗死患者前内侧梗死较孤立性桥脑梗死患者少，被盖区和单侧多发性梗死较多。
Background The topographic location of acute pontine infarction is associated with clinical syndromes and prognosis. Previous studies focused on isolated pontine infarction, but the topographic location of unisolated pontine infarction has remained unclear. Methods This was a prospective, multicenter, longitudinal registry study. Patients with acute pontine infarction confirmed by magnetic resonance imaging (MRI) were enrolled. Based on the territory of the pontine artery, the topographic location was divided into anteromedial, anterolateral, tegmental, bilateral and unilateral multiple infarctions. Results From May 1, 2003, to Oct 31, 2017, 1003 patients were enrolled, and 330 had unisolated pontine infarction. For isolated pontine infarction, 44.9, 19.8, 16.0, 13.1 and 6.2% of patients had anteromedial, anterolateral, tegmental, bilateral and unilateral multiple pontine infarctions, respectively. For unisolated pontine infarction, 30.3, 19.7, 24.5, 15.2 and 10.3% of patients had anteromedial, anterolateral, tegmental, bilateral and unilateral multiple pontine infarctions, respectively. Conclusion In this large series study, our data revealed fewer anteromedial infarctions and more tegmental and unilateral multiple infarctions in patients with unisolated pontine infarction than in patients with isolated pontine infarction.