Current management of Helicobacter pylori infection.
Current management of Helicobacter pylori infection.
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目前幽门螺杆菌感染的治疗。
DOI：
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发表时间：
2001
影响因子：
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通讯作者：
V. Mahachai
中科院分区：
文献类型：
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作者：
R. Vilaichone;V. Mahachai
幽门螺杆菌是一种常见的幽门螺杆菌。它与广泛的胃十二指肠疾病有关。关于特征性生物体、行为和相关临床状况的知识是广泛的。事实上，细菌并不是唯一的致病因素，宿主和环境因素也很重要。拉尔森，H.幽门螺杆菌在世界范围内消失，这是由于根除了这种微生物，使得H. pylori阴性的溃疡相对增加，可能更难治疗。PPI三联疗法仍然是一线治疗，四联疗法作为二线抢救。细菌耐药菌株的出现是一个新的问题，需要新的药物来提高现有方案的疗效。
Helicobacter pylori is commonly found throughout the world. It is associated with a wide range of gastroduodenal diseases. Knowledge regarding the characteristic organism, behaviour, and related clinical conditions is extensive. Indeed, the bacteria is not the only factor which can cause the diseases, the host as well as environmental factors are also important. Largely, H. pylori is disappearing worldwide due to eradication of this organism allowing frequency of an H. pylori negative ulcer to relatively increase and may be more difficult to treat. The PPI triple therapy remains the first line of treatment with quadruple therapy as the second rescue line. The rising of bacterial resistant strains is a new problem which requires new drugs to improve the efficacy of the current regimens.