Postnatal changes in pulmonary mechanics and energetics of infants with respiratory distress syndrome following surfactant treatment.
Postnatal changes in pulmonary mechanics and energetics of infants with respiratory distress syndrome following surfactant treatment.
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DOI：
10.1159/000084880
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发表时间：
2005-01-01
期刊：
影响因子：
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通讯作者：
Sivieri, Emidio M
中科院分区：
文献类型：
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作者：
Bhutani, Vinod K;Bowen, Frank W;Sivieri, Emidio M
背景：出生后肺力学、能量学和功能残气量(FRC)的变化描述了早产儿呼吸系统结构的成熟。目的：评估呼吸窘迫综合征(RDS)婴儿在氧气、正压通气和合成表面活性物质(Exosurf)治疗后肺功能的纵向变化。方法：对出生后接受表面活性物质治疗的婴儿[平均+/-SD出生体重(BW)=1,112+/-276 g，胎龄(GA)=29+/-3周]进行系列肺功能测试：
BACKGROUND: Postnatal alterations in pulmonary mechanics, energetics and functional residual capacity (FRC) describe the structural maturation of the preterm respiratory system.OBJECTIVE: To evaluate longitudinal changes in pulmonary function in infants with respiratory distress syndrome (RDS) treated with oxygen, positive pressure ventilation and synthetic surfactant (Exosurf).METHODS: Serial pulmonary function tests were performed in surfactant-treated infants [mean +/- SD birth weight (BW) = 1,112 +/- 276 g, gestational age (GA) = 29 +/- 3 weeks] at postnatal ages: