Laser-induced cavitation based micropump
Laser-induced cavitation based micropump
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DOI：
10.1039/b806912c
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发表时间：
2008-10-01
期刊：
影响因子：
6.1
通讯作者：
Ohl, Claus-Dieter
中科院分区：
文献类型：
--
作者：
Dijkink, Rory;Ohl, Claus-Dieter
片上实验室设备由于具有多功能且强大的泵送技术而受到强烈需求。在这里，我们提出了一种基于空化的技术，该技术能够在 75 μs 内泵送 4000 μ m(3) 的体积，预计压头为 3 bar。单个空化事件是通过将激光脉冲聚焦在靠近通道开口的传统 PDMS 微流体芯片中而产生的。 I 百万帧 s(-1) 的高速摄影解析了供应通道、泵通道和腔体附近的流动。材料的弹性影响整体流体流动，图中显示了以高达 5 Hz 的重复频率连续泵送通过 20 μm 宽的 6 mm 长方形通道。参数研究揭示了操作的关键参数：激光焦点和通道之间的距离、最大气泡尺寸和腔室几何形状。
Lab-on-a-chip devices are in strong demand as versatile and robust pumping techniques. Here, we present a cavitation based technique, which is able to pump a volume of 4000 mu m(3) within 75 mu s against an estimated pressure head of 3 bar. The single cavitation event is created by focusing a laser pulse in a conventional PDMS microfluidic chip close to the channel opening. High-speed photography at I million frames s(-1) resolves the flow in the supply channel, pump channel, and close to the cavity. The elasticity of the material affects the overall fluid flow Continuous pumping at repetition rates of up to 5 Hz through 6 mm long square channels of 20 mu m width is shown. A parameter study reveals the key-parameters for operation: the distance between the laser focus and the channel, the maximum bubble size, and the chamber geometry.