Directional movement of dendritic macromolecules on gradient surfaces
Directional movement of dendritic macromolecules on gradient surfaces
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DOI：
10.1021/nl070005v
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发表时间：
2007-04-01
期刊：
影响因子：
10.8
通讯作者：
Reinhoudt, David N.
中科院分区：
文献类型：
--
作者：
Chang, Theresa;Rozkiewicz, Dorota I.;Reinhoudt, David N.
已经开发出一种梯度驱动的方法来操纵树枝状大分子的运动。用罗丹明 B 标记的聚（丙烯亚胺）树枝状聚合物通过多个亚胺键连接到玻璃基板上。树枝状聚合物能够通过这些亚胺键的水解和重新形成在表面上移动。在没有外部刺激的情况下，这种随机运动会导致基材上的二维扩散。我们能够通过玻璃基板上的醛梯度来偏置这些纳米粒子的运动。
A gradient-driven methodology has been developed to manipulate the movement of dendritic macromolecules. Poly(propyleneimine) dendrimers, labeled with rhodamine B, are attached to glass substrates via multiple imine bonds. The dendrimers are able to move on the surface by the hydrolysis and re-formation of these imine bonds. In the absence of an external stimulus, this random movement results in a two-dimensional diffusion on the substrate. We are able to bias the movement of these nanoparticles by means of an aldehyde gradient on the glass substrate.