CONVERSION OF INJECTED GLUCOSE INTO RENAL GLYCOGEN AND MUCOPOLYSACCHARIDES - AN AUTORADIOGRAPHIC STUDY OF RABBITS IN VARIOUS STATES OF HYDRATION
CONVERSION OF INJECTED GLUCOSE INTO RENAL GLYCOGEN AND MUCOPOLYSACCHARIDES - AN AUTORADIOGRAPHIC STUDY OF RABBITS IN VARIOUS STATES OF HYDRATION
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DOI：
10.1007/bf00335505
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发表时间：
1969-01-01
期刊：
影响因子：
--
通讯作者：
DARNTON, SJ
中科院分区：
文献类型：
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作者：
DARNTON, SJ
将氚化葡萄糖注射到不同水合状态的家兔体内。所有动物的肾乳头都表现出对标签的摄取，转化为糖原和粘多糖，其方式取决于动物的水平衡。在对照动物乳头中，标记集管上皮细胞的糖原和间质粘多糖。在水利尿动物的乳头中，收集管糖原有轻微的标记，而间质上没有标记。抗利尿激素引起标签从集合管转移到间质粘多糖。这些发现的意义，就肾脏浓缩能力，讨论。
Tritiated glucose has been injected into rabbits in various states of hydration. The renal papilla of all animals showed an uptake of the label, converted into glycogen, and into mucopolysaccharides, in a manner dependent on the water balance of the animal.In papillae of control animals, the glycogen of the collecting duct epithelial cells and the mucopolysaccharides of the interstitium were labelled.In papillae of animals in an aqueous diuresis, the collecting duct glycogen was lightly labelled and there was no label over the interstitium.Antidiuretic hormone caused a diversion of label from the collecting ducts into interstitial mucopolysaccharides.The significance of these findings, with respect to renal concentrating ability, is discussed.