Novel ring B abeo-sterols as growth inhibitors of Mycobacterium tuberculosis isolated from a Caribbean Sea sponge, Svenzea zeai
Novel ring B abeo-sterols as growth inhibitors of Mycobacterium tuberculosis isolated from a Caribbean Sea sponge, Svenzea zeai
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DOI：
10.1016/j.tetlet.2007.10.070
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发表时间：
2007-12-10
影响因子：
1.8
通讯作者：
Franzblau, Scott G.
中科院分区：
文献类型：
--
作者：
Wei, Xiaomei;Rodriguez, Abimael D.;Franzblau, Scott G.
对从加勒比海海绵 Svenzea zeai 中获得的中等强度的抗结核提取物进行测定引导分馏，得到两种新型 5(6 -> 7) abeo-sterols，称为 parguesterols A (1) 和 B (2)，作为其活性成分。在广泛的光谱分析的基础上阐明了它们的结构。 (C) 2007 Elsevier Ltd. 保留所有权利。
Assay-guided fractionation of a moderately strong anti-tubercular extract obtained from the Caribbean Sea sponge Svenzea zeai afforded two novel 5(6 -> 7) abeo-sterols, named parguesterols A (1) and B (2), as its active components. Their structures were elucidated on the basis of extensive spectroscopic analysis. (C) 2007 Elsevier Ltd. All rights reserved.