Synthesis of Monophosphaferrocenes Revisited
Synthesis of Monophosphaferrocenes Revisited
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DOI：
10.1002/slct.202104472
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发表时间：
2022-01-21
期刊：
影响因子：
2.1
通讯作者：
Ogasawara, Masamichi
中科院分区：
文献类型：
--
作者：
Masaoka, Kakeru;Ohkubo, Manami;Ogasawara, Masamichi
重新研究了Roberts和威尔斯报道的制备单磷二茂铁的方法，该方法需要2当量的[（均三甲苯）FeCp] PF 6（A）。通过使用廉价的氯化铝作为苯基锂清除剂，可以实现所需A的50%降低。从相应的对苯基磷杂环戊二烯A（1当量），和氯化铝（1/3当量）。在修改后的条件下。这些改进的条件显示出与原始条件相比更好的单磷二茂铁产率和更好的原子经济性。
The method of preparing monophosphaferrocenes originally reported by Roberts and Wells, which requires two equivalents of [(mesitylene)FeCp]PF6 (A), was reinvestigated. By the use of inexpensive aluminum chloride as a phenyllithium scavenger, a 50 % reduction of required A could be attained. Diverse monophosphaferrocene derivatives having aliphatic C-substituents, including four new compounds, were prepared in good yields from the corresponding P-phenylphospholes, A (1 equiv.), and aluminum chloride (1/3 equiv.) under the modified conditions. These modified conditions showed comparable to better yields of monophosphaferrocenes and the far better atom-economy compared to the original conditions.