Validation of brief screening measures for depression and anxiety in young people with substance use disorders.
Validation of brief screening measures for depression and anxiety in young people with substance use disorders.
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DOI：
10.1016/j.jad.2021.01.005
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发表时间：
2021-03-01
影响因子：
6.6
通讯作者：
Yule AM
中科院分区：
文献类型：
--
作者：
Bentley KH;Sakurai H;Lowman KL;Rines-Toth L;McKowen J;Pedrelli P;Evins AE;Yule AM
及时识别和监测SUD年轻人的情绪和焦虑症状至关重要。本研究的主要目的是进行心理测量学验证的患者健康问卷（PHQ-9）和广泛性焦虑障碍量表（GAD-7）的抑郁和焦虑筛查寻求门诊治疗的年轻人SUD。我们的第二个目的是比较性能的PHQ-9和GAD-7，其简短的两个项目版本（PHQ-2和GAD-2）在检测可能的情绪和焦虑障碍。数据提取自在医院门诊SUD治疗项目中临床实施PHQ-9和GAD-7后接受诊断评价的患者（年龄14至26岁）的电子健康记录（N=121，平均年龄19.1 ± 3.1岁）。PHQ-9和GAD-7表现出良好的内部一致性。在这些数据中，PHQ-9切割评分为7或8（PHQ-2切割评分：2）和GAD-7切割评分为6（GAD-2切割评分：2）具有灵敏度、特异性和阳性和阴性预测能力的最佳平衡。这些措施也表现出良好的收敛性和可接受的判别效度。样本主要是白色和非西班牙裔，并验证（半）结构化诊断访谈不用于建立情绪和焦虑障碍的诊断。结果表明，PHQ-9和GAD-7是可靠的和潜在的临床有用的筛选工具，抑郁和焦虑的年轻人与SUD，和两个项目的版本可能有类似的临床实用性作为完整的措施。
It is critical to promptly identify and monitor mood and anxiety symptoms in young people with SUD. The primary aim of this study was to conduct a psychometric validation of the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder scale (GAD-7) for depression and anxiety screening in young people seeking outpatient treatment for SUD. Our secondary aim was to compare the performance of the PHQ-9 and GAD-7 to their briefer two-item versions (PHQ-2 and GAD-2) in terms of detecting probable mood and anxiety disorders. Data were extracted from the electronic health records of patients (ages 14 to 26) who received a diagnostic evaluation following clinical implementation of the PHQ-9 and GAD-7 at a hospital-based outpatient SUD treatment program (N=121, average age 19.1 ± 3.1 years). The PHQ-9 and GAD-7 showed excellent internal consistency. A PHQ-9 cut score of 7 or 8 (PHQ-2 cut score: 2) and GAD-7 cut score of 6 (GAD-2 cut score: 2) had the best balance of sensitivity, specificity, and positive and negative predictive power in these data. These measures also showed good convergent and acceptable discriminant validity. The sample was predominantly White and non-Hispanic, and a validated (semi-)structured diagnostic interview was not used to establish mood and anxiety disorder diagnoses. Results suggest the PHQ-9 and GAD-7 are reliable and potentially clinically useful screening tools for depression and anxiety in young people with SUD, and that the two-item versions may have similar clinical utility as the full measures.
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