Cancer cell metabolism: Warburg and beyond
Cancer cell metabolism: Warburg and beyond
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DOI:
10.1016/j.cell.2008.08.021
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发表时间:
2008-09-05
期刊:
影响因子:
64.5
通讯作者:
Sabatini, David M.
中科院分区:
文献类型:
--
作者:
Hsu, Peggy P.;Sabatini, David M.
Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg effect and establish a framework for understanding its contribution to the altered metabolism of cancer cells.