Patterns of osteocalcin and bone specific alkaline phosphatase by age, gender, and race or ethnicity
Patterns of osteocalcin and bone specific alkaline phosphatase by age, gender, and race or ethnicity
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DOI：
10.1016/s8756-3282(02)00902-x
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发表时间：
2002-12-01
期刊：
影响因子：
4.1
通讯作者：
Calvo, MS
中科院分区：
文献类型：
--
作者：
Gundberg, CM;Looker, AC;Calvo, MS
各种评估骨形成或骨吸收的骨转换生化标志物现在可用于研究和临床应用。然而，我们对这些措施在一般人群中随年龄增长的通常模式的了解有限。因此，两个骨形成标志物，血清骨钙素（Oc）和骨特异性碱性磷酸酶（骨ALP）的值进行了比较，年龄，性别，种族或民族使用的血清从子样本的黑人，白人，墨西哥裔美国人从第三次全国健康和营养调查（NHANES）。在所有种族和民族中，女性血清Oc和骨ALP的平均值均低于男性
A variety of biochemical markers of bone turnover that assess bone formation or resorption are now available for research and clinical application. However, our understanding of the usual pattern of these measures over age in the general population is limited. Therefore, values of two bone formation markers, serum osteocalcin (Oc) and bone specific alkaline phosphatase (bone ALP), were compared by age, gender, and race or ethnicity using serum obtained from a subsample of blacks, whites, and Mexican Americans from the third National Health and Nutrition Examination Survey (NHANES). In all racial and ethnic groups, mean values of both serum Oc and bone ALP were lower in women than in men