TRANSFUSION STUDIES IN RHEUMATOID ARTHRITIS

TRANSFUSION STUDIES IN RHEUMATOID ARTHRITIS
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DOI:
10.1002/art.1780040105
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发表时间:
1961-01-01
影响因子:
--
通讯作者:
VAUGHAN, JH
VAUGHAN, JH
中科院分区:
其他
文献类型:
--
作者:
HARRIS, J;VAUGHAN, JH

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已经进行了一系列的输血研究,其中血浆或血浆与外周血白细胞一起从类风湿关节炎患者输注到非类风湿受体。供者的血浆和白细胞都有很高的类风湿凝集活性。这些研究中没有迹象表明,输注类风湿因子复合体有能力在接受者中产生疾病,至少在这些实验的条件下是这样。在这些输血后的两到三年的随访中,仍然没有证据表明接受者发生了疾病。
A series of transfusion studies has been performed, in which either plasma or plasma together with peripheral leukocytes has been transfused from patients with rheumatoid arthritis into non-rheumatoid recipients. The donors of the plasma and leukocytes all had very high levels of rheumatoid agglutinating activity. There was no indication in these studies that transfusion of the rheumatoid factor complex has had ability to produce disease in the recipients, at least under the conditions of these experiments. In a two to three year follow-up after these transfusions, there was still no evidence of development of disease in the recipients.