ACOUSTIC INPUT TO LATERAL PONTINE NUCLEI
ACOUSTIC INPUT TO LATERAL PONTINE NUCLEI
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DOI：
10.1016/0378-5955(78)90010-2
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发表时间：
1978-01-01
期刊：
影响因子：
2.8
通讯作者：
BOYD, J
中科院分区：
文献类型：
--
作者：
AITKIN, LM;BOYD, J
本实验观察了猫下丘损毁后桥背外侧核（DLPN）内轴突和终末的变性。在单独的实验中，研究了111个单位的脑桥外侧核的声学反应在猫麻醉与氯醛尿烷。下丘所有3个核团（中央、中央周围和外部）的病变导致同侧DLPN离散区域中非常相似的终末变性模式，表明高度会聚投影，其中地形可能模糊。大多数单位响应双耳刺激。最常见的双耳反应包括兴奋性输入从每只耳朵促进在一些双耳强度水平和闭塞在其他。放电率从刺激开始时诱发的尖峰数量的改变而改变。持续放电很少遇到。单位广泛和不规则的调整;双耳抑制是非常罕见的。单位反应特征表明，虽然下丘的投射是高度会聚的，但可能只涉及下丘神经元的一个亚类。脑桥外侧单元的声学特性与小脑蚓部的声学特性惊人地相似，小脑蚓部是DLPN投射的区域。
Axon and terminal degeneration were studied in the cat dorsolateral pontine nucleus (DLPN) after lesion of the inferior colliculus. In separate experiments the acoustic responses of 111 units of the lateral pontine nuclei were studied in cats anesthetized with choralose-urethane. Lesions of all 3 nuclei of the inferior colliculus (central, pericentral and external) lead to a very similar pattern of terminal degeneration in a discrete region of ipsilateral DLPN, suggesting a highly convergent projection in which topography may be blurred. Most units responded to binaural stimulation. The most common binaural response consisted of excitatory inputs from each ear facilitated at some binaural intensity levels and occluded at others. Discharge rates changed from alterations in the number of spikes evoked at the onset of the stimulus. Sustained discharges were rarely encountered. Units were broadly and irregularly tuned; binaural inhibition was very uncommon. Unit response characteristics suggested, while the projection from the inferior colliculus was highly convergent, only a subclass of inferior colliculus neurons may be involved. The acoustic properties of lateral pontine units were strikingly similar to those of the cerebellar vermis, a region where DLPN is known to project.