A PROSPECTIVE-STUDY OF ACUTE CEREBROVASCULAR-DISEASE IN THE COMMUNITY - THE OXFORDSHIRE-COMMUNITY-STROKE-PROJECT 1981-86 .1. METHODOLOGY, DEMOGRAPHY AND INCIDENT CASES OF 1ST-EVER STROKE
A PROSPECTIVE-STUDY OF ACUTE CEREBROVASCULAR-DISEASE IN THE COMMUNITY - THE OXFORDSHIRE-COMMUNITY-STROKE-PROJECT 1981-86 .1. METHODOLOGY, DEMOGRAPHY AND INCIDENT CASES OF 1ST-EVER STROKE
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DOI：
10.1136/jnnp.51.11.1373
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发表时间：
1988-11-01
影响因子：
11
通讯作者：
WADE, D
中科院分区：
文献类型：
--
作者：
BAMFORD, J;SANDERCOCK, P;WADE, D
本文报告了一项在一个约105，000人的社区中进行的急性脑血管病的前瞻性研究。该研究方案结合了对患者的快速临床评估，以及通过CT或尸检准确诊断卒中的病理类型，无论患者是否入院。研究人群被定义为那些与50名合作全科医生（GP）之一注册的人。然而，该研究的参考文献主要来自全科医生，为了确保完整的病例确定，医院伤亡和入院登记，死亡证明和牛津记录连锁研究的特殊数据也进行了仔细审查。在4年内登记了675例临床确诊的首次终生卒中卡斯，根据1981年英格兰和威尔士人口调整后，得出粗年发病率为1.70/1000或2.00/1000。首次卒中的年龄和性别特异性发病率随年龄的增长而急剧上升。男性首次中风的几率比女性高26%。91%的患者在事件发生后4天内接受了研究神经科医生的检查，88%的患者进行了脑CT或尸检。
A prospective study of acute cerebrovascular disease in a community of about 105,000 people is reported. The study protocol combined rapid clinical assessment fo patients with accurate diagnosis of the pathological type of stroke by CT or necropsy, whether or not they were admitted to hospital. The study population was defined as those people who were registered with one of 50 collaborating general practitioners (GPs). Referrals to the study were primarily from the GPs though, to ensure complete case ascertainment, hospital casualty and admission registers, death certificates and special data from the Oxford Record Linkage Study were also scrutinised. Six hundred and seventy five cass of clinically definite first-ever in a lifetime stroke were registered in four years yielding a crude annual incidence fo 1.70/1,000 or 2.00/1,000 when adjusted to the 1981 population of England and Wales. The age and sex specific incidence rates for first stroke showed a steep rise with age for both sexes. The odds of a male sustaining a first stroke were 26% greater than those of a female. Ninety one per cent of patients were examined in a median time of four days after the event by a study neurologist and 88% had cerebral CT or necropsy.