Intrasellar pleomorphic xanthoastrocytoma: Case report

Intrasellar pleomorphic xanthoastrocytoma: Case report
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DOI:
10.1097/00006123-200210000-00042
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发表时间:
2002-10-01
期刊:
影响因子:
4.8
通讯作者:
Hirose, T
Hirose, T
中科院分区:
医学1区
文献类型:
--
作者:
Arita, K;Kurisu, K;Hirose, T

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OBJECTIVE AND IMPORTANCE: A patient with a primary intrasellar pleomorphic xanthoastrocytoma is described.CLINICAL PRESENTATION: A 78-year-old woman experienced slowly progressing bilateral visual disturbance. Analysis of magnetic resonance imaging scans indicated a well-enhanced tumor occupying intra- and suprasellar spaces with displacement of the pituitary gland anteriorly,INTERVENTION: Partial resection of the tumor via the transsphenoidal route brought about improvement of the, patient's,visual disturbance. The tumor was conspicuously pleomorphic and composed of plump to spindle-shaped large and bizarre cells with single or multiple nuclei and lipid-laden foamy cytoplasm. The neoplastic cells were positive for glial fibrillar acidic protein, S-100 protein, and vimentin. The MIB-1 antibody labeling index was very low (