Amino acid sequences of a hyperglycaemic hormone and its related peptides from the Kuruma prawn, Penaeus japonicus
Amino acid sequences of a hyperglycaemic hormone and its related peptides from the Kuruma prawn, Penaeus japonicus
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日本对虾高血糖激素及其相关肽的氨基酸序列
DOI：
10.1016/0044-8486(95)01015-7
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发表时间：
1995
期刊：
影响因子：
4.5
通讯作者：
H. Nagasawa
中科院分区：
文献类型：
--
作者：
Wei;K. Aida;H. Nagasawa
主要的肽已提取的库鲁马对虾，对虾窦腺，并通过反相高效液相色谱纯化到均匀。根据肽的氨基末端序列和质谱分析以及生物测定的结果，其中一种肽被认为是高血糖激素。肽的完整氨基酸序列已确定;它由72个氨基酸残基组成，并具有酰胺化羧基末端。其他四个肽的序列分析显示，它们都是结构相关的高血压激素。发现所有这些肽都是由单个个体产生的。
Major peptides have been extracted from sinus glands of the Kuruma prawn, Penaeus japonicus, and purified to homogeneity by reverse-phase HPLC. From the results of amino-terminal sequence and mass spectral analyses and bioassay of the peptides, one of the peptides was considered to be a hyperglycaemic hormone. The complete amino acid sequence of the peptide has been determined; it consists of 72 amino acid residues and has an amidated carboxyl-terminus. Sequence analyses of the other four peptides revealed that they all were structurally related to the hyperglycaemic hormone. All of these peptides were found to be produced by a single individual.