Alzheimer's Disease : Advances in Genetics, Molecular and Cellular Biology
Alzheimer's Disease : Advances in Genetics, Molecular and Cellular Biology
复制标题
DOI：
--
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
S. Sisodia;R. Tanzi
中科院分区：
文献类型：
--
作者：
S. Sisodia;R. Tanzi
老年痴呆症的遗传学APP生物学，加工和功能。早老素复合物的生物学。?-分泌酶：生理作用和目标验证。转基因A？和阿尔茨海默病的Tau模型。胆固醇和？淀粉样蛋白A？结构和聚合。介导A？诱发神经功能障碍。β淀粉样蛋白和兴奋性突触。A？堕落。- A的作用？运输和清除的发病机制和治疗阿尔茨海默病。FTDP-17合成酶中的Tau基因突变Tauopathy的动物模型Tau和轴突运输阿尔茨海默病的治疗方法
The Genetics of Alzheimer's Disease.- APP Biology, Processing and Function.- The Biology of the Presenilin Complexes.- ?-secretase: Physiological Role and Target Validation.- Cognitive Impairment in Transgenic A? and Tau Models of Alzheimer's Disease.- Cholesterol and ?-Amyloid.- A? Structure and Aggregation.- Signaling Mechanisms that Mediate A? Induced Neuronal Dysfunction.- Beta Amyloid and Excitatory Synapses.- A? Degradation.- Role of A ? Transport and Clearance in the Pathogenesis and Treatment of Alzheimer's Disease.- Tau Gene Mutations in FTDP-17 Syndromes.- Animal Models of Tauopathy.- Tau and Axonal Transport.- Growth Factors in Alzheimer's Disease.