The Zebrafish Information Network (ZFIN): the zebrafish model organism database

The Zebrafish Information Network (ZFIN): the zebrafish model organism database
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DOI:
10.1093/nar/gkg027
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发表时间:
2003-01-01
影响因子:
14.9
通讯作者:
Westerfield, M
Westerfield, M
中科院分区:
生物学2区
文献类型:
--
作者:
Sprague, J;Clements, D;Westerfield, M

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斑马鱼信息网络(ZFIN)是一个基于网络的社区资源,作为管理和整合斑马鱼遗传、基因组和发育数据的集中位置。ZFIN可在http://zfin.org公开访问。ZFIN提供了突变体、基因、遗传标记、制图面板、出版物和社区联系数据的集成表示。ZFIN最近的改进包括:(i)一个解剖学词典,它提供了解剖学术语的受控词汇,按发育阶段分组,可用于注释和查询基因表达数据;(ii)基因表达数据;(iii)扩大对基因组序列的支持;(iv)使用基因本体(\GO)术语的标准化词汇进行基因注释,可用于阐明斑马鱼和其他生物的基因产物之间的关系;(v)与其他数据库(NCBI、Sanger研究所和SWISS-PROT)合作,在共享管理的基础上提供标准化和互联。
The Zebrafish Information Network (ZFIN) is a web based community resource that serves as a centralized location for the curation and integration of zebrafish genetic, genomic and developmental data. ZFIN is publicly accessible at http://zfin.org. ZFIN provides an integrated representation of mutants, genes, genetic markers, mapping panels, publications and community contact data. Recent enhancements to ZFIN include: (i) an anatomical dictionary that provides a controlled vocabulary of anatomical terms, grouped by developmental stages, that may be used to annotate and query gene expression data; (ii) gene expression data; (iii) expanded support for genome sequence; (iv) gene annotation using the standardized vocabulary of Gene Ontology ( \GO) terms that can be used to elucidate relationships between gene products in zebrafish and other organisms; and (v) collaborations with other databases (NCBI, Sanger Institute and SWISS-PROT) to provide standardization and interconnections based on shared curation.