Three-dimensional cerebral vasculature of the CBA mouse brain: A magnetic resonance imaging and micro computed tomography study
Three-dimensional cerebral vasculature of the CBA mouse brain: A magnetic resonance imaging and micro computed tomography study
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DOI：
10.1016/j.neuroimage.2006.12.040
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发表时间：
2007-05-01
期刊：
影响因子：
5.7
通讯作者：
Kabani, N.
中科院分区：
文献类型：
--
作者：
Dorr, A.;Sled, J. G.;Kabani, N.
到目前为止，对小鼠脑血管系统的研究主要集中在Willis环，而没有研究穿过大脑其余部分的血管的形态分布。由于小鼠模型经常用于脑相关研究，因此需要一份全面的小鼠脑血管图谱，重点放在血管相对于神经解剖结构的位置、与特定动脉相关的分水岭区域以及脑血管的一致命名。本文描述了这样一种图谱，它基于磁共振和计算机断层扫描技术的结合，在CBA小鼠身上产生高分辨率的体积和血管数据。这一三维血管系统数据集为未来的小鼠研究提供了解剖学资源。(C)2006 Elsevier Inc.保留所有权利。
Studies of mouse cerebral vasculature to date have focused on the circle of Willis without examining the morphological distribution of blood vessels through the rest of the brain. Since mouse models are frequently used in brain-related studies, there is a need for a comprehensive cerebral vasculature atlas for the mouse with an emphasis on the location of vessels with respect to neuroanatomical structures, the watershed regions associated with specific arteries, as well as a consistent nomenclature of the cerebral vessels. This article describes such an atlas, based on a combination of magnetic resonance and computed tomography technology to yield high-resolution volumetric and vasculature data on CBA mouse. This three-dimensional vasculature dataset provides an anatomical resource for future mouse studies. (c) 2006 Elsevier Inc. All rights reserved.