ACR classification criteria for systemic lupus erythematosus: complement components
ACR classification criteria for systemic lupus erythematosus: complement components
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DOI：
10.1191/0961203304lu2027oa
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发表时间：
2004-01-01
期刊：
影响因子：
2.6
通讯作者：
Sturfelt, G
中科院分区：
文献类型：
--
作者：
Nived, O;Sturfelt, G
补体参与系统性红斑狼疮（SLE）的发病机制，并且在疾病的发展中也具有看似矛盾的保护作用。低水平的补体经典途径中的组分，尤其是C1q、C4和C3，对SLE诊断具有高特异性，应被认为是有希望纳入SLE分类标准的。
Complement is involved in the pathogenesis of systemic lupus erythematosus (SLE) and has also a seemingly paradoxical protective role in the development of the disease. Low levels of components within the classical pathway of complement especially C1q, C4 and C3 have a high specificity for SLE diagnosis and should be considered as promising for inclusion in classification criteria of SLE.