Differential engagement of anterior cingulate cortex subdivisions for cognitive and emotional function
Differential engagement of anterior cingulate cortex subdivisions for cognitive and emotional function
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DOI：
10.1111/j.1469-8986.2007.00515.x
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发表时间：
2007-05-01
期刊：
影响因子：
3.7
通讯作者：
Miller, Gregory A.
中科院分区：
文献类型：
--
作者：
Mohanty, Aprajita;Engels, Anna S.;Miller, Gregory A.
背侧（dACC）和吻侧（rACC）前扣带皮层的认知和情感功能的功能分化已经得到了相当多的间接支持。本研究采用功能磁共振成像、平行任务和受试者内分析，直接测试了ACC细分的专业化。一个任务x区域的互动证实更多的dACC激活在颜色词分心和更多的rACC激活在情绪词分心。活动在ACC细分差异预测行为表现。与前额叶和边缘区的连接也支持不同的dACC和rACC的作用。研究结果提供了直接的证据，差异参与的ACC细分在认知和情绪处理和差异功能连接的认知控制和情绪调节的实施。结果表明，解剖和功能的连续性，而不是分离的操作。
Functional differentiation of dorsal (dACC) and rostral (rACC) anterior cingulate cortex for cognitive and emotional function has received considerable indirect support. Using fMRI, parallel tasks, and within-subject analysis, the present study directly tested the proposed specialization of ACC subdivisions. A Task x Region interaction confirmed more dACC activation during color-word distractors and more rACC activation during emotion-word distractors. Activity in ACC subdivisions differentially predicted behavioral performance. Connectivity with prefrontal and limbic regions also supported distinct dACC and rACC roles. Findings provide direct evidence for differential engagement of ACC subdivisions in cognitive and emotional processing and for differential functional connectivity in the implementation of cognitive control and emotion regulation. Results point to an anatomical and functional continuum rather than segregated operations.