Exploring the Aldol Reaction in the Synthesis of Bioactive Compounds
Exploring the Aldol Reaction in the Synthesis of Bioactive Compounds
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DOI：
10.1002/chin.201617267
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发表时间：
2015-09
影响因子：
1.8
通讯作者：
M. Ferreira;Luiz C. Dias;Ives A. Leonarczyk;E. Polo;E. C. D. Lucca
中科院分区：
文献类型：
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作者：
M. Ferreira;Luiz C. Dias;Ives A. Leonarczyk;E. Polo;E. C. D. Lucca
羰基化学，特别是醛醇反应，是构建碳-碳键最有效、最优雅的策略之一。在过去的15年里，在巴西，我们的研究小组和其他人一直致力于立体选择性醛醇反应的开发和应用，并直接应用于几种具有生物学意义的天然产物的不对称合成。在这次审查中，我们强调巴西对这一领域的主要贡献。
Carbonyl chemistry, specifically aldol reactions, is one of the most efficient and elegant strategies to build carbon-carbon bonds. In the last 15 years in Brazil, our research group and others have worked on the development and application of stereoselective aldol reactions, with direct application in the asymmetric synthesis of several natural products of biological interest. In this review, we highlight the major Brazilian contributions to this field.