Pazopanib for second recurrence of osteosarcoma in pediatric patients

Pazopanib for second recurrence of osteosarcoma in pediatric patients
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DOI:
10.1111/ped.13307
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发表时间:
2017-08-01
影响因子:
1.4
通讯作者:
Adachi, Souchi
Adachi, Souchi
中科院分区:
医学4区
文献类型:
--
作者:
Umeda, Katsutsugu;Kato, Itaru;Adachi, Souchi

文献摘要

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本文介绍了帕佐帕尼治疗儿童骨肉瘤(OS)二次复发的病例。讨论的主题包括观察血清碱性磷酸酶(ALP)的升高;借助计算机断层扫描(CT)检测肝内肿瘤大小的NO变化;以及与帕佐帕尼相关的不良反应的信息。
The article presents cases of pediatric patients with osteosarcoma (OS) treated with pazopanib for second recurrence. Topics discussed include observation of the elevated serum alkaline phosphatase (ALP); detection of no changes in the size of intrahepatic tumors with the help of computed tomography (CT); and information on adverse effects associated with pazopanib.