Symptoms and problems in a nationally representative sample of advanced cancer patients
Symptoms and problems in a nationally representative sample of advanced cancer patients
复制标题
DOI：
10.1177/0269216309105400
复制
发表时间：
2009-09-01
影响因子：
4.4
通讯作者：
Groenvold, M.
中科院分区：
文献类型：
--
作者：
Johnsen, A. T.;Petersen, M. A.;Groenvold, M.
对于没有接受专科姑息治疗的晚期癌症患者，对姑息治疗的需求了解甚少。目的是确定具有全国代表性的丹麦晚期癌症患者样本中症状和问题的患病率和预测因素。来自54个医院科室的3期或4期癌症患者（n = 1630）接受了EORTC QLQ-C30问卷调查。根据评分手册计算平均分数，并定义和计算“症状/问题”和“严重症状/问题”。采用多元逻辑回归识别预测因子。共有977例（60%）患者参与。最常见的症状/问题是疲劳（57%；严重的22%），其次是角色功能下降、失眠和疼痛。年龄、癌症分期、原发肿瘤、科室类型、婚姻状况以及患者最近是否住院与若干症状和问题有关。这可能是同类研究中第一个具有全国代表性的研究。它表明，丹麦晚期癌症患者的症状和问题值得关注，一些患者群体尤其处于危险之中。缓和医学（2009）；23日:491 - 501
Little is known about the need for palliative care among advanced cancer patients who are not in specialist palliative care. The purpose was to identify prevalence and predictors of symptoms and problems in a nationally representative sample of Danish advanced cancer patients. Patients with cancer stage 3 or 4 from 54 hospital departments (n = 1630) received the EORTC QLQ-C30 questionnaire. Mean scores were calculated according to the scoring manual and in addition a 'symptom/problem' and a 'severe symptom/problem' was defined and calculated. Multiple logistic regression was used to identify predictors. In total, 977 (60%) patients participated. The most frequent symptoms/problems were fatigue (57%; severe 22%) followed by reduced role function, insomnia and pain. Age, cancer stage, primary tumour, type of department, marital status and whether the patient had recently been hospitalized or not were associated with several symptoms and problems. This is probably the first nationally representative study of its kind. It shows that advanced cancer patients in Denmark have symptoms and problems that deserve attention and that some patient groups are especially at risk. Palliative Medicine (2009); 23: 491-501