Histological changes in the articular eminence and mandibular fossa during growth of the rhesus monkey (Macaca mulatta).
Histological changes in the articular eminence and mandibular fossa during growth of the rhesus monkey (Macaca mulatta).
复制标题
恒河猴（Macaca mulatta）生长过程中关节隆起和下颌窝的组织学变化。
DOI：
10.1002/aja.1001660108
复制
发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Carlson,DS
中科院分区：
文献类型：
--
作者：
Hinton,RJ;Carlson,DS
与下颌骨髁突不同，颞下颌关节 (TMJ) 的颞部部分对其生长和重塑的研究相对较少。该报告提供了恒河猴（Macaca mulatta）生长过程中下颌窝和关节隆起的显微解剖变化的定性和定量记录。对 43 只恒河猴的五个成熟水平（新生儿、婴儿、青少年、青少年和青年）的纤维关节组织的厚度及其深层软骨细胞的存在进行了组织学检查。在所有研究区域中，关节组织的绝对厚度随着成熟水平的增加而增加，其中关节隆起的后坡和嵴的增加比下颌窝的顶部更明显。相对于髁大小，关节层厚度的增加是前三个成熟阶段的特征，随后在青少年和年轻成人阶段减少。随着年龄的增长，窝顶的关节组织占总关节组织厚度的比例逐渐减小，而后坡和隆起顶部的组织的相对厚度则随着年龄的增长而增加。这些结果与下颌髁突获得的结果相似，并且最好将它们解释为表明传递到关节的力随着年龄的增长而变得更加向前。关节组织厚度和软骨细胞分布的地形变化的总体模式表明，不同研究人员在人类颞下颌关节中假设的颞下颌关节外侧负荷更大，但在猴子中可能并不那么明显。
Unlike the mandibular condyle, the temporal component of the temporomandibular joint (TMJ) has been the object of relatively few investigations concerning its growth and remodeling. This report provides qualitative and quantitative documentation of microanatomical changes in the mandibular fossa and articular eminence during growth of the rhesus monkey (Macaca mulatta). The thickness of the fibrous articular tissue and the presence of cartilage cells in its deeper layers were examined histologically in 43 rhesus monkeys at five maturational levels (neonate, infant, juvenile, adolescent, and young adult). Absolute thickness of the articular tissue increased with maturational level in all areas studied, with the increase somewhat more pronounced on the posterior slope and crest of the articular eminence than in the roof of the mandibular fossa. Relative to condylar size, an increase in articularlayer thickness characterized the first three maturational levels, and was followed by a decrease during adolescent and young‐adult stages. Articular tissue in the fossa roof constituted a steadily decreasing fraction of the total articular‐tissue thickness with age, while relative thickness of the tissue on the posterior slope and crest of the eminence increased with age. These results parallel those obtained for the mandibular condyle, and they are best interpreted to indicate that forces delivered to the joint become directed more anteriorly with age. The overall pattern of topographical variation in articular‐tissue thickness and cartilage‐cell distribution suggests that greater loading of the lateral aspect of the TMJ, postulated in the human TMJ by various workers, may not be as pronounced in the monkey.