The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges
The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges
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DOI：
10.2214/ajr.16.16355
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发表时间：
2017-01-01
影响因子：
5
通讯作者：
Haider, Masoom A.
中科院分区：
文献类型：
--
作者：
Barrett, Tristan;Haider, Masoom A.
目标。主动监测(AS)已成为预防惰性前列腺癌过度治疗的一种管理策略。传统上证明，AS患者的选择具有挑战性，并导致20%-30%的错分率。MRI有可能帮助克服这一局限，拓宽选择标准以增加招募，并将AS的侵袭性降至最低。结论：围绕MRI和AS的主要问题是纳入标准的异质性，重大疾病的定义，以及对什么构成放射学进展的一致。为了进一步解决这些问题，需要在登记时进行核磁共振的前瞻性队列研究和长期随访。
OBJECTIVE. Active surveillance (AS) has emerged as a management strategy for preventing overtreatment of indolent prostate cancer. Selection of patients for AS has traditionally proved challenging and resulted in 20-30% misclassification rates. MRI has potential to help overcome this limitation, broaden selection criteria to increase recruitment, and minimize the invasive nature of AS follow-up.CONCLUSION. The main issues surrounding MRI and AS are the heterogeneity of inclusion criteria, the definition of significant disease, and agreement about what constitutes radiologic progression. Prospective cohorts with MRI at enrollment and long-term follow-up are required to further address these issues.