Sensitive and Fast Humidity Sensor Based on A Redox Conducting Supramolecular Ionic Material for Respiration Monitoring
Sensitive and Fast Humidity Sensor Based on A Redox Conducting Supramolecular Ionic Material for Respiration Monitoring
复制标题
基于氧化还原导电超分子离子材料的灵敏快速湿度传感器，用于呼吸监测
DOI：
10.1021/acs.analchem.6b04350
复制
发表时间：
2017
影响因子：
7.4
通讯作者：
Mao Lanqun
中科院分区：
文献类型：
--
作者：
Yan Hailong;Zhang Li;Yu Ping;Mao Lanqun
实时监测呼吸频率（RR）对于人体健康、临床诊断和基础科学研究具有重要意义。基于呼气湿度的RR监测最近因其准确性和便携性而引起越来越多的关注。在这里，我们报告了一种新的设计的呼气湿度传感器的实时监测的RR的基础上合成的氧化还原导电超分子离子材料（SIM）。采用离子自组装技术，在具有电活性的2，2 ′-连氮双（3-乙基苯并噻唑-6-磺酸）（ABTS）和1，10-双（3-甲基咪唑-1-基）癸烷（C10（mim）2）水溶液中制备了湿度依赖型导电SIM.通过充分利用由两个结构单元之间的离子和疏水相互作用产生的高吸湿性和水稳定性（即，ABTS和C10（mim）2），基于SIM的湿度传感器具有高灵敏度（相对湿度小于0.1%）和快速响应时间（± 37 ms）。这些优异的特性使该湿度传感器不仅可以无创地监测人类的RR，还可以监测比人类快得多的RR和小得多的潮气量的大鼠。此外，该传感器还可以有效地用于实时监测大鼠从麻醉中恢复的过程。
Real-time monitoring of respiratory rate (RR) is highly important for human health, clinical diagnosis, and fundamental scientific research. Exhaled humidity-based RR monitoring has recently attracted increased attention because of its accuracy and portability. Here, we report a new design of an exhaled humidity sensor for the real-time monitoring of the RR based on a synthetic redox conducting supramolecular ionic material (SIM). The humidity-dependent conducting SIM is prepared by ionic self-assembly in aqueous solutions of electroactive 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,10-bis(3-methylimidazolium-1-yl) decane (C10(mim)2). By taking full advantage of the high hygroscopicity and water stability arising from the ionic and hydrophobic interactions between two building blocks (i.e., ABTS and C10(mim)2), the SIM-based humidity sensor exhibits both high sensitivity (less than 0.1% relative humidity) and fast response time (∼37 ms). These excellent properties allow this humidity sensor to noninvasively monitor the RRs of not only humans but also rats that have a much faster RR and much smaller tidal volume than humans. Moreover, this sensor could also be efficiently used for the real-time monitoring of the recovery process of rats from anesthesia.