Sorbitol Concentration in the Plasma and Erythrocytes of Diabetic Subjects
Sorbitol Concentration in the Plasma and Erythrocytes of Diabetic Subjects
复制标题
糖尿病受试者血浆和红细胞中的山梨醇浓度
DOI：
10.2337/diacare.5.3.319
复制
发表时间：
1982
期刊：
影响因子：
16.2
通讯作者：
W. Malaisse
中科院分区：
文献类型：
--
作者：
G. Somers;I. Depoorter;A. Sener;W. Malaisse
Sorbitol content of plasma and red blood cells is increased in diabetic subjects, and it correlates with plasma glucose concentration. Rapid changes in plasma glucose concentration, either during normalization or impairment of glucose homeostasis, are paralleled by equally rapid changes in plasma or erythrocyte sorbitol content. At variance with a recent proposal, it is concluded that the measurement of sorbitol in red cells is not a reliable indicator of either long-term blood glucose levels or sorbitol accumulation in those tissues in which such an accumulation participates in the pathogenesis of degenerative Complications.
