DNA Damage from Pulsed Sonication of Human Leukocytes In Vitro

DNA Damage from Pulsed Sonication of Human Leukocytes In Vitro
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体外人类白细胞脉冲超声处理造成的 DNA 损伤

DOI：
10.1109/t-uffc.1986.26812
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发表时间：
1986
期刊：
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control
影响因子：
--
通讯作者：
A. Rossi
A. Rossi
中科院分区：
--
文献类型：
--
作者：
S. Pinamonti;A. Caruso;V. Mazzeo;E. Zebini;A. Rossi

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脉冲回声超声人类白细胞在体外导致延迟反应PHA生殖刺激和损伤的DNA。从超声细胞中分离的DNA的电泳迁移率、对核酸酶S1的敏感性和电子显微镜分析强烈表明，脉冲超声导致体外DNA单链断裂。
Pulsed echo sonication of human leukocytes in vitro results in a delayed response to the PHA reproductive stimulus and in damage to the DNA. The electrophoretic mobility, the sensitivity to nuclease S1 and the electron microscopy analysis of the DNA isolated from sonicated cells strongly suggest that pulsed ultrasound causes in vitro single strand breaks in DNA.