Flagellar Shock Responses in Green Algae
Flagellar Shock Responses in Green Algae
复制标题
绿藻的鞭毛休克反应
DOI：
10.1111/j.1438-8677.1995.tb00847.x
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发表时间：
1995
影响因子：
4
通讯作者：
G. Kreimer
中科院分区：
文献类型：
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作者：
G. Kreimer
The basic structural and functional components of eukaryotic flagella are widely conserved despite the large diversity of flagella-bearing cells. During flagellar beating, dynein-mediated microtubule sliding is converted by elastic and viscous resistances to bending of the flagella. To propagate a bend along the flagellum the activity of the force-generator dynein is internally controlled in a cyclic way, both around the outer ring of axonemal microtubules and along the length of the axoneme. It is now emerging that different dyneins within the axoneme may have specific functions in the control of flagellar bending, although the conversion of their inherent self-oscillatory activity into the observed coordinated sliding-bending is still enigmatic. In addition to intrinsic control mechanisms within the axoneme, changes in the concentration of second messengers like Ca2+ and cyclic nucleotides are intricately involved in the various flagellar responses (reviews: Witman, 1990; Brokaw, 1994; Tamm, 1994). Among the different model organisms, the flagellar apparatus of the unicellular green alga Chlamydomonas reinhardtii is one of the best studied systems. This is mainly due to the accessibility of C. rein-hardtii to genetic manipulation, the presence of a great variety of mutants, the ease of growth of physiologically and genetically identical populations in large quantities, and its capacity of flagellar regeneration (Goodenough, 1992; Johnson and Rosenbaum, 1993; Gumpel and Purton, 1994).C. reinhardtii and other green algae respond to various external stimuli with peculiar motility changes. Of these, the photoresponses with their rhodopsin-based receptor belong to the best studied and have attracted the interest of scientists over decades (for recent reviews see: Witman, 1993; Kreimer, 1994). During forward swimming of the cell (Fig. 1, box) the two flagella move in an asymmetric, breast-stroke type beat pattern with 43-63 Hz. The
影响因子：
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作者：
KREIMER, G;WITMAN, GB
通讯作者：
WITMAN, GB