The frequency and seasonality of influenza and other respiratory viruses in Tennessee: two influenza seasons of surveillance data, 2010-2012.
The frequency and seasonality of influenza and other respiratory viruses in Tennessee: two influenza seasons of surveillance data, 2010-2012.
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DOI：
10.1111/irv.12145
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发表时间：
2013-11
影响因子：
4.4
通讯作者：
Smalley DL
中科院分区：
文献类型：
--
作者：
Landes MB;Neil RB;McCool SS;Mason BP;Woron AM;Garman RL;Smalley DL
2010年，田纳西州卫生部与疾病控制和预防中心（CDC）合作，将田纳西州的流感监测范围扩大到包括其他呼吸道病毒。目的：确定2010-2012年流感季节流感和其他呼吸道病毒的流行率和季节性。在田纳西州收集流感样疾病患者的鼻拭子和鼻咽拭子/洗涤液。使用基于分子的呼吸道病毒面板鉴定流感病毒和其他呼吸道病毒。根据CDC方案，采用实时PCR对A型流感阳性进行分型。对数据进行分析，以描述流行菌株的频率和季节性。在933份阳性标本中，流感病毒检出率为60.3%，鼻病毒/肠道病毒检出率为19.8%，呼吸道合胞病毒（RSV）检出率为8.6%，偏肺病毒检出率为5.8%，腺病毒检出率为3.0%，副流感病毒检出率为2.5%。在2010-2011年流感季节，乙型流感在48-3周突出，而甲型H1N1流感在4-10周最常见。甲型流感（H3N2）在第48-17周出现较低水平。然而，在2011-2012年流感季节，流感病例总数减少，甲型流感（H3N2）是最丰富的流感毒株。对其他呼吸道病毒的扩大监测注意到，从第一季到第二季，腺病毒、偏肺病毒、RSV和鼻病毒/肠道病毒的鉴定标本有所增加。本研究提供了在田纳西州流行的流感毒株的数据。它还建立了一个基线和一年中的时间来预测其他呼吸道病毒，这将有助于发现田纳西州非流感呼吸道病毒的爆发。
In 2010, the Tennessee Department of Health, in collaboration with the Centers for Disease Control and Prevention (CDC), expanded influenza surveillance in Tennessee to include other respiratory viruses. To determine the prevalence and seasonality of influenza and other respiratory viruses during the influenza seasons of 2010–2012. Nasal and nasopharangeal swabs/washings from persons with influenza‐like illness were collected across Tennessee. Influenza and other respiratory viruses were identified using a molecular‐based respiratory virus panel. Influenza A positives were subtyped using real‐time PCR according to the CDC protocol. Data were analyzed to describe frequency and seasonality of circulating strains. Of the 933 positive specimens, 60·3% were identified as influenza viruses, 19·8% rhinovirus/enterovirus, 8·6% respiratory syncytial virus (RSV), 5·8% metapneumovirus, 3·0% adenovirus, and 2·5% parainfluenza viruses. In the 2010–2011 season, influenza B was prominent during weeks 48–3, while influenza A(H1N1) was most frequently identified during weeks 4–10. Influenza A(H3N2) was present at lower levels during weeks 48–17. However, in the 2011–2012 season, overall numbers of influenza cases were reduced and influenza A (H3N2) was the most abundant influenza strain. The expanded surveillance for other respiratory viruses noted an increase in identified specimens from the first to the second season for adenovirus, metapneumovirus, RSV, and rhinovirus/enterovirus. This study provides data of the influenza strains in circulation in Tennessee. It also establishes a baseline and time of year to expect other respiratory viruses that will aid in detecting outbreaks of non‐influenza respiratory viruses in Tennessee.