Contribution of stratum corneum in determining bio-tribological properties of the human skin
Contribution of stratum corneum in determining bio-tribological properties of the human skin
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DOI：
10.1016/j.wear.2007.01.128
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发表时间：
2007-09
期刊：
影响因子：
5
通讯作者：
C. Pailler-Mattéi;S. Pavan;R. Vargiolu;F. Pirot;F. Falson;H. Zahouani
中科院分区：
文献类型：
--
作者：
C. Pailler-Mattéi;S. Pavan;R. Vargiolu;F. Pirot;F. Falson;H. Zahouani
本文研究了角质层对人体皮肤生物摩擦学性能的影响。首先，纳米压痕和纳米摩擦测试实现了离体上孤立SC。结果表明，孤立SC表现为梯度材料在最深的方向。此外，我们证明了SC的机械性能显着不同于整个皮肤。体内摩擦学测试是用专门为软材料开发的原始摩擦计（压痕和摩擦）实现的。这些结果在体内证实了从人体皮肤中去除SC（通过连续的胶带剥离），这主要表现为探针和皮肤表面之间的粘附力的增加和在没有SC的情况下的侧向刚度的降低。总之，我们表明，SC包括一个摩擦粘附组件，影响整体摩擦皮肤行为。
The present study deals with the impact of stratum corneum (SC) on the human skin bio-tribological properties. First, the nano-indentation and nano-friction tests were realised ex vivo onto isolated SC. The results showed that isolated SC behaved as a gradient material in the deepest direction. Furthermore, we demonstrated that the mechanical properties of SC differ markedly from those of whole skin. The in vivo tribological tests were realised with an original tribometer (indentation and friction), specially developed for the soft materials. These results were confirmed in vivo by the removal of SC from human skin (by successive tape-stripping), which showed principally an increase of the adhesion force between the probe and the skin surface and a decrease of the lateral stiffness in absence of SC. In conclusion, we showed that SC comprises a friction adhesion component which influences the overall frictional skin behaviour.