Visions for regenerative medicine: interface between scientific fact and science fiction.

Visions for regenerative medicine: interface between scientific fact and science fiction.
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再生医学的愿景:科学事实与科幻小说之间的界面。

DOI:
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发表时间:
2006
期刊:
影响因子:
2.4
通讯作者:
Ronald E. Unger
Ronald E. Unger
中科院分区:
工程技术3区
文献类型:
--
作者:
C. Kirkpatrick;S. Fuchs;K. Peters;C. Brochhausen;M. Hermanns;Ronald E. Unger

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本文就组织工程对材料科学和生命科学的挑战,对组织工程的未来发展提出了自己的看法。重点将放在三维生物可吸收聚合物与相关分子线索和自体干细胞或祖细胞的应用相结合的优势。在对外界刺激作出反应的所谓“智能”材料的合成以及新型药物和基因传递系统的开发方面,需要有更多的多样性。此外,在发育生物学以及现代细胞和分子生物学在生物材料问题上的应用方面,还需要进行更多的基础研究。
This article gives a brief overview of the authors' views on the future development of tissue engineering with respect to the challenges both to the materials and life sciences. Emphasis will be placed on the advantages of three-dimensional bioresorbable polymers in combination with relevant molecular cues and the application of autologous stem or progenitor cells. There is a requirement for much more diversity in the synthesis of so-called "intelligent" materials, which respond to external stimuli, as well as the development of novel drug and gene delivery systems. In addition, much more basic research is necessary in developmental biology and the application of modern cell and molecular biology to biomaterial questions.
DOI: 10.1016/s0070-2153(04)60004-4
发表时间: 2004
影响因子: --
作者:
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智能聚合物-链霉亲和素缀合物。
DOI: 10.1385/1-59259-813-7:037
发表时间: 2004
期刊: Methods in molecular biology (Clifton, N.J.)
影响因子: --
作者:
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通讯作者: Hoffman,AllanS