Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the international study of asthma and allergies in childhood (ISAAC)
Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the international study of asthma and allergies in childhood (ISAAC)
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DOI：
10.1111/j.1399-3038.1997.tb00156.x
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发表时间：
1997-11-01
影响因子：
4.4
通讯作者：
Williams, HC
中科院分区：
文献类型：
--
作者：
Strachan, DP;Sibbald, B;Williams, HC
背景资料：作为儿童哮喘和过敏症国际研究（ISAAC）的一部分，对来自欧洲、亚洲、非洲、澳大拉西亚、北美洲和南美洲的学龄儿童代表性样本进行了患病率调查。来自38个国家的91个中心的257，800名6-7岁儿童和来自56个国家的155个中心的463，801名13-14岁儿童。将书面症状问卷从英语翻译成当地语言，由13-14岁的儿童自行完成，并由6-7岁儿童的父母完成。鼻炎被描述为一个问题，打喷嚏，或流鼻涕，或鼻子堵塞时，你（你的孩子）没有感冒或流感。其他问题被问及鼻炎与发痒，水汪汪的眼睛，干扰活动和花粉热的历史every.Results：鼻炎与发痒，水汪汪的眼睛（“鼻结膜炎”）在过去的一年中的患病率各不相同，从0.8%至14.9%的6-7岁的孩子和1.4%至39.7%的13-14岁的孩子。在每个年龄组内，每个症状类别的全球模式大致一致。在流行率较高的中心，被标记为花粉热的鼻结膜炎的比例差异很大。东欧、南亚和中亚部分地区的鼻结膜炎发病率最低。高患病率的报告，从中心在几个regions.Conclusion：这些结果表明，过敏性鼻结膜炎的症状，需要进一步研究的患病率和标签在世界范围内的变化。这些差异，如果是真实的，可能会为环境对过敏的影响提供重要线索。
Background: As part of the International Study of Asthma and Allergies in Childhood (ISAAC), prevalence surveys were conducted among representative samples of school children from locations in Europe, Asia, Africa, Australasia, North and South America.Subjects: 257,800 children aged 6-7 years from 91 centres in 38 countries, and 463,801 children aged 13-14 years from 155 centres in 56 countries.Methods: Written symptom questionnaires were translated from English into the local language for self-completion by the 13-14-year-olds and completion by the parents of the 6-7-year-olds. Rhinitis was described as a problem with sneezing, or a runny, or blocked nose when you (your child) DID NOT have a cold or the 'flu. Additional questions were asked about rhinitis associated with itchy-watery eyes, interference with activities and a history of hay fever ever.Results: The prevalence of rhinitis with itchy-watery eyes ("rhinoconjunctivitis") in the past year varied across centres from 0.8% to 14.9% in the 6-7-year-olds and from 1.4% to 39.7% in the 13-14-year-olds. Within each age group, the global pattern was broadly consistent across each of the symptom categories. In centres of higher prevalence there was great variability in the proportion of rhinoconjunctivitis labelled as hay fever. The lowest prevalences of rhinoconjunctivitis were found in parts of eastern Europe, south and central Asia. High prevalences were reported from centres in several regions.Conclusion: These results suggest substantial worldwide variations in the prevalence and labelling of symptoms of allergic rhinoconjunctivitis which require further study. These differences, if real, may offer important clues to environmental influences on allergy.