Expansion of seasonal influenza vaccination in the Americas
Expansion of seasonal influenza vaccination in the Americas
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DOI：
10.1186/1471-2458-9-361
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发表时间：
2009-09-24
影响因子：
4.5
通讯作者：
Andrus, Jon K.
中科院分区：
文献类型：
--
作者：
Ropero-Alvarez, Alba Maria;Kurtis, Hannah J.;Andrus, Jon K.
工作背景：季节性流感是一种病毒性疾病，其每年的流行估计在全世界造成300万至500万例严重疾病和25万至50万例死亡。疫苗接种是一级prevention.Methods的主要策略：为了评估在美洲的流感疫苗接种的状态，流感疫苗接种数据报告给泛美卫生组织（PAHO）通过2008年进行了analyzed.Results：35个国家和地区管理流感疫苗在其公共卫生部门，相比，在2004年的13个国家。目标风险群体各不相同。16个国家报告了老年人的覆盖率，从21%到100%不等;大多数国家和目标人群的覆盖率数据不详。一些热带国家使用北方半球疫苗制剂，其他国家使用南半球疫苗制剂。2008年，在美洲购买了大约1.663亿剂季节性流感疫苗; 35个国家中有30个通过泛美卫生组织的循环基金购买了疫苗。全面实施流感疫苗接种的挑战依然存在，包括难以衡量覆盖率、疫苗接种情况不一、监测和有效性数据有限，无法指导疫苗配方和接种时机的决定，特别是在热带国家。
Background: Seasonal influenza is a viral disease whose annual epidemics are estimated to cause three to five million cases of severe illness and 250,000 to 500,000 deaths worldwide. Vaccination is the main strategy for primary prevention.Methods: To assess the status of influenza vaccination in the Americas, influenza vaccination data reported to the Pan American Health Organization (PAHO) through 2008 were analyzed.Results: Thirty-five countries and territories administered influenza vaccine in their public health sector, compared to 13 countries in 2004. Targeted risk groups varied. Sixteen countries reported coverage among older adults, ranging from 21% to 100%; coverage data were not available for most countries and targeted populations. Some tropical countries used the Northern Hemisphere vaccine formulation and others used the Southern Hemisphere vaccine formulation. In 2008, approximately 166.3 million doses of seasonal influenza vaccine were purchased in the Americas; 30 of 35 countries procured their vaccine through PAHO's Revolving Fund.Conclusion: Since 2004 there has been rapid uptake of seasonal influenza vaccine in the Americas. Challenges to fully implement influenza vaccination remain, including difficulties measuring coverage rates, variable vaccine uptake, and limited surveillance and effectiveness data to guide decisions regarding vaccine formulation and timing, especially in tropical countries.