Synthesis of crosslinked peptidoglycan fragments for investigation of their immunobiological functions
Synthesis of crosslinked peptidoglycan fragments for investigation of their immunobiological functions
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DOI：
10.1016/j.tetlet.2009.03.081
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发表时间：
2009-07-01
影响因子：
1.8
通讯作者：
Fukase, Koichi
中科院分区：
文献类型：
--
作者：
Fujimoto, Yukari;Konishi, Yasuko;Fukase, Koichi
以肺炎链球菌细胞壁为原料合成交联肽聚糖片段。还测定了免疫刺激活性，包括诱导IL-6和刺激细胞内受体Nod2。交联的PGN片段不是主要的人类Nod2配体。2009爱思唯尔有限公司版权所有。
The synthesis of crosslinked peptidoglycan (PGN) fragments from Streptococcus pneumoniae cell wall was achieved. The immunostimulatory activities, including the induction of IL-6 and the stimulation of the intracellular receptor Nod2, were also determined. The crosslinked PGN fragments were not major human Nod2 ligands. (C) 2009 Elsevier Ltd. All rights reserved.