The second generation HRRT - a multi-centre scanner performance investigation
The second generation HRRT - a multi-centre scanner performance investigation
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第二代 HRRT - 多中心扫描仪性能调查
DOI：
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
D. Wong
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文献类型：
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作者：
V. Sossi;H. de Jong;W. Barker;P. Bloomfield;Z. Burbar;M. Camborde;C. Comtat;L. Eriksson;S. Houle;D. Keator;C. Knob;R. Krais;A. Lammertsma;A. Rahmim;M. Sibomana;M. Teras;C. Thompson;R. Trébossen;J. Votaw;M. Walker;K. Wienhard;D. Wong
高分辨率研究断层扫描仪（HRRT）是现有的最复杂的正电子发射断层扫描仪之一：它是唯一的人类大小的扫描仪能够解码的深度/spl γ/-射线在晶体中的相互作用，使用镥LSO/LYSO phoswich检测器安排。在这项研究中，我们确定了基本的扫描仪硬件特征，如扫描仪数据采集的稳定性，以及它们在11个中心的变异性。此外，还进行了NEMA NU-2001标准测量的一个子集。我们发现（i）DOI解码结果在中心之间的显著变化，（ii）作为从扫描仪校准起经过的时间的函数的检测到的真实重合事件的数量增加的趋势，这可能是由于移位的能谱，（iii）依赖于计数率的层识别，（iv）散射分数范围从/spl/sim/ 42%到54%，其中可变性部分地与能谱的移动有关，（v）各中心的灵敏度范围为/spl sim/5.5%至6.5%，（vi）各中心的分辨率为/spl sim/（2.5 mm）/sup 3/，相当一致，（vii）图像质量与其他扫描仪非常相似。
The high resolution research tomograph (HRRT) is one of the most complex existing positron emission tomographs: it is the only human size scanner capable of decoding the depth of the /spl gamma/-ray interaction in the crystal, using a lutetium LSO/LYSO phoswich detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from /spl sim/ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from /spl sim/5.5% to 6.5% across centres, (vi) resolution of /spl sim/(2.5 mm)/sup 3/, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.