The HMMTOP transmembrane topology prediction server
The HMMTOP transmembrane topology prediction server
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DOI：
10.1093/bioinformatics/17.9.849
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发表时间：
2001-09-01
期刊：
影响因子：
5.8
通讯作者：
Simon, I
中科院分区：
文献类型：
--
作者：
Tusnády, GE;Simon, I
HMMTOP跨膜拓扑预测服务器预测螺旋跨膜片段的定位和跨膜蛋白的拓扑。最近，对原始方法进行了一些改进。现在，允许用户提交关于片段定位的附加信息以增强预测能力。该选项提高了预测准确度，并有助于解释实验结果，即在表位插入实验中。
The HMMTOP transmembrane topology prediction server predicts both the localization of helical transmembrane segments and the topology of transmembrane proteins. Recently, several improvements have been introduced to the original method. Now, the user is allowed to submit additional information about segment localization to enhance the prediction power. This option improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments.