Polymorphous low‐grade (terminal duct) adenocarcinoma of the parotid gland
Polymorphous low‐grade (terminal duct) adenocarcinoma of the parotid gland
复制标题
腮腺多形性低级别（终末导管）腺癌
DOI：
10.1111/j.1365-2559.1991.tb01505.x
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发表时间：
1991
期刊：
影响因子：
6.4
通讯作者：
J. Miliauskas
中科院分区：
文献类型：
--
作者：
J. Miliauskas
肉眼可见腮腺内有一个边界清楚但无包膜的灰白色至棕褐色肿块20x16x10 mm。显微镜下，肿瘤边缘可见散在分布的浸润性病灶，并延伸至邻近腮腺。没有真正的胶囊存在。生长方式包括实心巢、管状/导管区、微乳头状灶和筛状或假腺样囊性区域(图1)。间质局限性玻璃化，其他区域略有纤维化。无肿瘤坏死或神经周围浸润，无伴发多形性腺瘤。细胞相对均匀，胞浆稀少至中等，胞核圆形至椭圆形，染色质较细，核仁较小。有丝分裂样稀少。
Macroscopically, the parotid gland contained a circumscribed but unencapsulated, grey/white to tan mass 20 x 16 x 10 mm. Microscopically, the tumour margins were partly circumscribed with scattered infiltrative foci, extending into the adjacent parotid gland. No true capsule was present. The growth patterns included solid nests, tubular/ductal areas, micropapillary foci and a cribriform or pseudo-adenoid cystic area (Figure 1). The stroma was focally hyalinized and somewhat fibrous in other areas. There was no tumour necrosis or perineural infiltration and no associated pleomorphic adenoma. The cells were relatively uniform with scant to moderate amounts of cytoplasm, round to oval nuclei with a fine chromatin pattern and small nucleoli. Mitotic figures were scant.