Cancer and Obesity: Effect of Bariatric Surgery
Cancer and Obesity: Effect of Bariatric Surgery
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DOI：
10.1007/s00268-009-0169-1
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发表时间：
2009-10-01
影响因子：
2.6
通讯作者：
Hunt, Steven C.
中科院分区：
文献类型：
--
作者：
Adams, Ted D.;Hunt, Steven C.
最近的国际癌症预防指南建议在适当的情况下减肥，以降低癌症风险。然而，有限的研究将自愿减肥与随后的癌症发病率联系起来，因为在大型参与者群体中难以实现长期减肥。减肥手术已经证明了长期持续的体重减轻，因此，减肥手术后的患者代表了一个理想的人群，以探索长期，自愿减肥和癌症发病率之间的关系。本文简要回顾了与超重和肥胖相关的癌症，并研究了减肥手术后总死亡率降低的研究。降低癌症死亡率和发病率，以及减少减肥手术后癌症相关的医生就诊。研究的局限性和未来的研究问题，有关癌症和减肥手术进行了简要讨论。
Recent international cancer prevention guidelines recommend weight loss, where appropriate, for the purpose of cancer risk reduction. However, limited research associates voluntary weight loss to subsequent cancer incidence because of the difficulty of achieving long-term weight loss maintenance among large participant groups. Bariatric surgery has demonstrated long-term sustained weight loss, and as a result, patients after bariatric surgery represent an ideal population to explore the relationship between long-term, voluntary weight loss and cancer incidence. This paper briefly reviews cancers that have shown to be associated with overweight and obesity and looks at studies that demonstrate reduced total mortality after bariatric surgery. Reduced cancer mortality and incidence as well as reduced cancer-related physician visits after bariatric surgery are presented. Study limitations and future research questions related to cancer and bariatric surgery are briefly discussed.