ACUTE EFFECTS OF A WINTER AIR-POLLUTION EPISODE ON PULMONARY-FUNCTION AND RESPIRATORY SYMPTOMS OF CHILDREN
ACUTE EFFECTS OF A WINTER AIR-POLLUTION EPISODE ON PULMONARY-FUNCTION AND RESPIRATORY SYMPTOMS OF CHILDREN
复制标题
DOI：
10.1080/00039896.1993.9936721
复制
发表时间：
1993-09-01
期刊：
影响因子：
--
通讯作者：
BRUNEKREEF, B
中科院分区：
文献类型：
--
作者：
HOEK, G;BRUNEKREEF, B
本文对112名7-12岁的非城市社区儿童进行了冬季空气污染急性呼吸道效应的研究。在第6天进行肺功能测定，连续测试之间的固定间隔为3 wk。在空气污染事件期间，进行了额外的肺功能测试。在日记中记录了儿童的急性呼吸道症状。二氧化硫、黑烟、空气动力学直径小于10 μ m的颗粒物和二氧化氮的环境浓度被认为是暴露变量。分别采用个体线性回归分析和时间序列分析评价空气污染与肺功能和急性呼吸道症状患病率的关系。在1991年2月，空气污染事件发生期间，每天平均二氧化硫浓度略高于100 μ g/m3，颗粒物（空气动力学直径小于10 μ m）浓度达到174 μ g/m3。在发作期间，用力肺活量、1秒用力呼气量和最大呼气中期流量低于基线测试。二氧化硫、黑烟和空气动力学直径小于10 μ m的颗粒物的浓度之间存在显著的负相关。急性呼吸道症状的流行率和这些化合物的浓度之间没有关联。
The acute respiratory effects of a wintertime air pollution episode were studied in a general population sample of 112 children who were 7-12 y of age and who lived in a nonurban community. Spirometry was performed on 6 d, with a fixed interal of 3 wk between successive tests. During an air pollution episode, an additional pulmonary function test was made. Acute respiratory symptoms of the children were noted in a diary. Ambient concentrations of sulfur dioxide, black smoke, particulate matter with an aerodynamic diameter less than 10 mum, and nitrogen dioxide were considered as exposure variables. The association of air pollution with pulmonary function and prevalence of acute respiratory symptoms was assessed by individual linear regression analysis and time series analysis, respectively. In February 1991, an air pollution episode occurred during which daily average sulfur dioxide concentrations were slightly above 100 mug/m3, and particulate matter (with an aerodynamic diameter of less than 10 mum) concentrations reached 174 mug/m3. During the episode, forced vital capacity, forced expiratory volume in 1 s, and maximal mid-expiratory flow were lower than on baseline tests. Significant negative associations were found between the concentration of sulfure dioxide, black smoke, and particulate matter with an aerodynamic diameter of less than 10 mum. No association between prevalence of acute respiratory symptoms and the concentration of these compounds was found.